Association between lipid accumulation product and non-alcoholic fatty liver disease with normal weight: a population-based study
Our study reveals a non-linear association between the LAP and the risk of NAFLD in individuals of normal weight, with LAP demonstrating superior predictive accuracy compared to BMI and WC. These results advocate for the use of LAP thresholds to guide early lifestyle interventions during metabolically reversible stages and to improve the identification of high-risk lean individuals who may be overlooked by current BMI-based screening methods.
Authors
- Linghong Shen (ORCID: https://orcid.org/0000-0001-7943-2030)
- Hui Peng (ORCID: https://orcid.org/0000-0002-7673-3919)
- Weifeng Chen (ORCID: https://orcid.org/0000-0001-9948-5826)
- Yuanfang Lin (ORCID: https://orcid.org/0009-0000-2638-6659)
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Shenzhen Second People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-08-20
- DOI
- https://doi.org/10.3389/fmed.2025.1565997
- Citations
- 3
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.06
Funders
- Sanming Project of Medicine in Shenzhen