Association between lipid accumulation product and non-alcoholic fatty liver disease with normal weight: a population-based study

Our study reveals a non-linear association between the LAP and the risk of NAFLD in individuals of normal weight, with LAP demonstrating superior predictive accuracy compared to BMI and WC. These results advocate for the use of LAP thresholds to guide early lifestyle interventions during metabolically reversible stages and to improve the identification of high-risk lean individuals who may be overlooked by current BMI-based screening methods.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-08-20
DOI
https://doi.org/10.3389/fmed.2025.1565997
Citations
3
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
4.06

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article

Association between lipid accumulation product and non-alcoholic fatty liver disease with normal weight: a population-based study

Linghong Shen, Hui Peng, Weifeng Chen, Yuanfang Lin
3 citations
Frontiers in Medicine
Liver Disease Diagnosis and Treatment
4.06
article

Association between lipid accumulation product and non-alcoholic fatty liver disease with normal weight: a population-based study

Linghong Shen, Hui Peng, Weifeng Chen, Yuanfang Lin
article en
3 citations

Abstract

Our study reveals a non-linear association between the LAP and the risk of NAFLD in individuals of normal weight, with LAP demonstrating superior predictive accuracy compared to BMI and WC. These results advocate for the use of LAP thresholds to guide early lifestyle interventions during metabolically reversible stages and to improve the identification of high-risk lean individuals who may be overlooked by current BMI-based screening methods.

Frontiers in MedicineVol. 12
Guangzhou University of Chinese Medicine (CN), Shenzhen Second People's Hospital (CN)
Sanming Project of Medicine in Shenzhen
Openalex Percentile: Top 6%
Liver Disease Diagnosis and Treatment
4.06
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