Disulfidptosis-associated gene signature predicts prognosis and radioresistance in NSCLC

Our findings imply that a prognostic model related to disulfidptosis could distinguish the prognostic differences among patients, allowing for more personalized treatment strategies. The mechanisms of KIF14 may provide a basis for combating radioresistance and a better understanding of the interaction between disulfidptosis and radiotherapy.

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Publication Details

Journal
Translational Oncology
Published
2025-08-20
DOI
https://doi.org/10.1016/j.tranon.2025.102496
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Disulfidptosis-associated gene signature predicts prognosis and radioresistance in NSCLC

Jia Wang, Meng Wu, Dawei Chen, Juan Wang et al.
Translational Oncology
Ferroptosis and cancer prognosis
article

Disulfidptosis-associated gene signature predicts prognosis and radioresistance in NSCLC

Jia Wang, Meng Wu, Dawei Chen, Juan Wang, Jinming Yu, Jianmin Liu
article en

Abstract

Our findings imply that a prognostic model related to disulfidptosis could distinguish the prognostic differences among patients, allowing for more personalized treatment strategies. The mechanisms of KIF14 may provide a basis for combating radioresistance and a better understanding of the interaction between disulfidptosis and radiotherapy.

Translational OncologyVol. 61
Weifang Medical University (CN), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Shandong First Medical University (CN)
Zero hunger
Openalex Percentile: Top 68%
Ferroptosis and cancer prognosis
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