Burden of Helicobacter pylori in Duodenal Ulcer Disease: Evidence From a Tertiary Hospital in Chennai, India

This research highlights the high burden of <i>H. pylori</i> among duodenal ulcer patients in Chennai. Regional risk factors, including diet, hygiene, and medication use, contribute significantly to infection prevalence. Quadruple therapy showed superior efficacy in the eradication and prevention of recurrence. These findings support the need for routine screening, region-specific treatment protocols, and targeted public health interventions to control <i>H. pylori</i>-related gastroduodenal disease.