Exploratory study on the potential benefits of prophylactic levetiracetam after acute spontaneous intracerebral hemorrhage

The routine use of seizure prophylaxis with levetiracetam did not result in a significant reduction in early seizure incidence, and in unadjusted analyses, the prophylaxis group had longer ICU and hospital stays. However, these differences were not significant after adjustment for key clinical confounders. Randomized controlled trials need to be conducted to determine whether seizure prophylaxis with levetiracetam contributes to worse outcomes.