Methodological issue in a dental neuromelioidosis outbreak investigation

Thirugnanakumar and colleagues1 provided critical genomic evidence linking a neuromelioidosis cluster in Tamil Nadu to iatrogenic transmission via contaminated saline at a dental clinic.1 The identification of B. pseudomallei ST1553 with the bimABmBm allele in both clinical (brain tissue) and environmental (saline bottle) isolates unravelled a novel transmission route. The high fatality (80%) underscores severe neurovirulence concerns. While pivotal in revealing a novel transmission route, several aspects warrant further scientific discussion:

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Publication Details

Journal
The Lancet Regional Health - Southeast Asia
Published
2025-08-20
DOI
https://doi.org/10.1016/j.lansea.2025.100658
Citations
1
Primary Topic
Tailings Management and Properties
Type
article
Field-Weighted Citation Impact
0.95
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article

Methodological issue in a dental neuromelioidosis outbreak investigation

Bijayini Behera, PrasantaR Mohapatra
1 citations
The Lancet Regional Health - Southeast Asia
Tailings Management and Properties
0.95
article

Methodological issue in a dental neuromelioidosis outbreak investigation

Bijayini Behera, PrasantaR Mohapatra
article en
1 citations

Abstract

Thirugnanakumar and colleagues1 provided critical genomic evidence linking a neuromelioidosis cluster in Tamil Nadu to iatrogenic transmission via contaminated saline at a dental clinic.1 The identification of B. pseudomallei ST1553 with the bimABmBm allele in both clinical (brain tissue) and environmental (saline bottle) isolates unravelled a novel transmission route. The high fatality (80%) underscores severe neurovirulence concerns. While pivotal in revealing a novel transmission route, several aspects warrant further scientific discussion:

The Lancet Regional Health - Southeast AsiaVol. 43
All India Institute of Medical Sciences Bhubaneswar (IN)
Openalex Percentile: Top 22%
Tailings Management and Properties
0.95
DOIOpen Access PDFOpenAlex
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