Proliferation of Tumor-Related Regulatory T Cells in Circulation Dictates Efficacy of Chemoimmunotherapy in Triple-Negative Breast Cancer
Our results indicate that the proliferation and expansion of tumor-related clonotypes among circulating Treg are related to chemoimmunotherapy resistance, particularly in TNBC.
Authors
- Eun Kyung Cho (ORCID: https://orcid.org/0000-0003-0593-4841)
- Eui‐Cheol Shin (ORCID: https://orcid.org/0000-0002-6308-9503)
- Koung Jin Suh (ORCID: https://orcid.org/0000-0002-1881-8738)
- Milim Kim (ORCID: https://orcid.org/0000-0001-6966-1606)
- Eui-Soon Kim (ORCID: https://orcid.org/0000-0003-2313-8646)
- Joohyuk Sohn (ORCID: https://orcid.org/0000-0002-2303-2764)
- Seung Hyuck Jeon (ORCID: https://orcid.org/0000-0001-8227-9452)
- Kyung Hae Jung (ORCID: https://orcid.org/0000-0002-1580-7224)
- In Sil Choi (ORCID: https://orcid.org/0000-0002-8494-584X)
- Se Hyun Kim (ORCID: https://orcid.org/0000-0002-2292-906X)
- Seock‐Ah Im (ORCID: https://orcid.org/0000-0002-5396-6533)
- Min Hwan Kim (ORCID: https://orcid.org/0000-0002-1595-6342)
- Minwoo Jeon (ORCID: https://orcid.org/0000-0002-5600-6714)
- Sungmin Jung (ORCID: https://orcid.org/0000-0002-3397-1837)
- Jee Hyun Kim (ORCID: https://orcid.org/0000-0003-1336-3620)
- So Yeon Park (ORCID: https://orcid.org/0000-0002-0299-7268)
- Yeon Hee Park (ORCID: https://orcid.org/0000-0003-4156-9212)
- Kyoung Eun Lee (ORCID: https://orcid.org/0000-0003-1596-8666)
- Jae Ho Jeong (ORCID: https://orcid.org/0000-0002-8749-2612)
- Hee Jun Kim (ORCID: https://orcid.org/0000-0002-2388-0552)
- Kyung-Hun Lee (ORCID: https://orcid.org/0000-0002-2390-3240)
- Ho Cheol Jang (ORCID: https://orcid.org/0009-0000-1155-2298)
Institutions
- Ulsan College (KR)
- Ewha Womans University (KR)
- Seoul National University (KR)
- Korea Advanced Institute of Science and Technology (KR)
- Yonsei University (KR)
- Severance Hospital (KR)
- Seoul Metropolitan Government (KR)
- Asan Medical Center (KR)
- Samsung Medical Center (KR)
- Seoul National University Hospital (KR)
- Seoul National University Bundang Hospital (KR)
- University of Ulsan (KR)
- Gachon University Gil Medical Center (KR)
- Gangnam Severance Hospital (KR)
- Chonnam National University Hwasun Hospital (KR)
- Chung-Ang University (KR)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2025-08-20
- DOI
- https://doi.org/10.1158/1078-0432.ccr-24-3283
- Citations
- 1
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.05