Mendelian randomization study of self-reported long sleep duration, short sleep duration, and insomnia and cognitive function
This study suggests self-reported short sleep duration was causally associated with cognitive decline and self-reported insomnia was causally associated with increased risk of Alzheimer's disease in individuals of European ancestry. The evidence of causality between long sleep duration and cognitive function requires further investigation. These results may have implications for public health interventions aimed at reducing the risk of cognitive decline.
Authors
- Yunyun Guo (ORCID: https://orcid.org/0009-0009-4572-1139)
Institutions
- Imperial College London (GB)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-08-20
- DOI
- https://doi.org/10.1371/journal.pone.0330782
- Primary Topic
- Sleep and related disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00