Synthesis and crystal structure of (<i>Z</i>)-2-(6-chloroimidazo[1,2-<i>a</i>]pyridin-2-yl)-3-[4-(dimethylamino)phenyl]acrylonitrile
The structure of the title compound, C<sub>18</sub>H<sub>15</sub>ClN<sub>4</sub>, was determined at low temperature (100 K). In the crystal, the mol-ecules are connected through C-H⋯N and C-H⋯Cl inter-molecular hydrogen bonds generating a network that extend along the [010] direction. In addition, C-H⋯π and π-π stacking inter-actions as well as inter-molecular contacts contribute to the cohesion of the structure. Hirshfeld surface analysis indicates that the contributions to the surface for the H⋯H, H⋯N/ N⋯H, H⋯C/C⋯H, H⋯Cl/Cl⋯H and C⋯C contacts are 30.2, 19.9, 28.6, 12.2 and 3.7%, respectively.
Authors
- Eric Ziki (ORCID: https://orcid.org/0009-0002-0130-4463)
- Jean-Paul Déto Ursul N'Guessan (ORCID: https://orcid.org/0000-0003-2440-2090)
- Ludovic Akonan (ORCID: https://orcid.org/0000-0003-1166-1050)
- Songuigama Coulibaly (ORCID: https://orcid.org/0000-0002-6795-0807)
- Mahama Ouattara (ORCID: https://orcid.org/0000-0003-0920-9399)
- Viviane Adohi-Krou
Institutions
- Université Nangui Abrogoua (CI)
- Université Félix Houphouët-Boigny (CI)
Publication Details
- Journal
- Acta Crystallographica Section E Crystallographic Communications
- Published
- 2025-08-15
- DOI
- https://doi.org/10.1107/s2056989025007248
- Primary Topic
- Synthesis and biological activity
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Centre National de la Recherche Scientifique