First Reported Case of Lower Extremity Wound Care with Incidental Myositis Ossificans: Traumatic/Posttraumatic/Circumscripta and an Extensive Literature Review

Abstract Myositis ossificans (MO) is a complex disease characterized by heterotopic bone growth, which can be challenging to diagnose as it may mimic other neoplastic abnormalities in its early stages. Its presentation is often obscured by other disease processes, making it a condition that arises from inflammatory processes gone awry and is frequently difficult to treat. The literature suggests supportive therapy and a cautious approach to surgical intervention, including debridements, unless contractures or limitations in range of motion or daily activities are affected beyond acceptable levels. In this paper, we aim to present a case study that provides clinicians with the most current information on MO and its subtypes, including pathological presentations, radiographic findings, and laboratory data to facilitate early diagnosis. We also propose state-of-the-art treatment methods and identify areas for much-needed investigative research. Our hope is that this paper will assist clinicians in making early diagnoses, ultimately helping patients afflicted with this often debilitating disease recover with less costly treatment options.

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Journal
Journal of Bone and Joint Diseases
Published
2025-05-01
DOI
https://doi.org/10.4103/jbjd.jbjd_6_25
Primary Topic
Heterotopic Ossification and Related Conditions
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article
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article

First Reported Case of Lower Extremity Wound Care with Incidental Myositis Ossificans: Traumatic/Posttraumatic/Circumscripta and an Extensive Literature Review

Frank Louis Lepore
Journal of Bone and Joint Diseases
Heterotopic Ossification and Related Conditions
article

First Reported Case of Lower Extremity Wound Care with Incidental Myositis Ossificans: Traumatic/Posttraumatic/Circumscripta and an Extensive Literature Review

Frank Louis Lepore
article en

Abstract

Abstract Myositis ossificans (MO) is a complex disease characterized by heterotopic bone growth, which can be challenging to diagnose as it may mimic other neoplastic abnormalities in its early stages. Its presentation is often obscured by other disease processes, making it a condition that arises from inflammatory processes gone awry and is frequently difficult to treat. The literature suggests supportive therapy and a cautious approach to surgical intervention, including debridements, unless contractures or limitations in range of motion or daily activities are affected beyond acceptable levels. In this paper, we aim to present a case study that provides clinicians with the most current information on MO and its subtypes, including pathological presentations, radiographic findings, and laboratory data to facilitate early diagnosis. We also propose state-of-the-art treatment methods and identify areas for much-needed investigative research. Our hope is that this paper will assist clinicians in making early diagnoses, ultimately helping patients afflicted with this often debilitating disease recover with less costly treatment options.

Journal of Bone and Joint DiseasesVol. 40(2)
Imaging the World (US)
Openalex Percentile: Top 67%
Heterotopic Ossification and Related Conditions
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First Reported Case of Lower Extremity Wound Care with Incidental Myositis Ossificans: Traumatic/Posttraumatic/Circumscripta and an Extensive Literature Review — Frank Louis Lepore · Journal of Bone and Joint Diseases (2025) | TGRS Research Map | TGRS