Increased risk of cardiac death with cumulative exposure to fluid overload and dialysate sodium ≤138 mmol/l in hemodialysis patients
Cumulative FO and dialysate sodium ≤138 mmol/l significantly increase cardiac death risk in hemodialysis patients, particularly from heart failure. Stringent fluid management and careful consideration of dialysate sodium prescription is crucial to reduce cardiovascular mortality.
Authors
- Brendan Smyth (ORCID: https://orcid.org/0000-0003-1838-3348)
- J Pintér (ORCID: https://orcid.org/0009-0007-8261-2586)
- Bernd Genser (ORCID: https://orcid.org/0000-0001-5787-0902)
- Stefano Stuard (ORCID: https://orcid.org/0000-0002-9546-4507)
- Bernard Canaud (ORCID: https://orcid.org/0000-0001-6854-2816)
- Kaitlin J. Mayne (ORCID: https://orcid.org/0000-0002-5695-0270)
- Martin Christa (ORCID: https://orcid.org/0000-0002-8703-7644)
Institutions
- Goethe University Frankfurt (DE)
- The University of Sydney (AU)
- Cooperative Trials Group for Neuro-Oncology (AU)
- Accadis Hochschule Bad Homburg (DE)
- Northwest Hospital (US)
- St George Hospital (AU)
- Universitätsklinikum Würzburg (DE)
- Heidelberg Engineering (Germany) (DE)
- University Hospital Frankfurt (DE)
- St. George Hospital (IN)
- National Health and Medical Research Council (AU)
- University of Glasgow (GB)
Publication Details
- Journal
- Clinical Kidney Journal
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1093/ckj/sfaf259
- Citations
- 1
- Primary Topic
- Dialysis and Renal Disease Management
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- Fresenius Medical Care North America
- Deutsche Forschungsgemeinschaft