Doxycycline Post-exposure Prophylaxis and Off-target Antimicrobial Resistance: Potential Amplification Within Sexual Networks

Doxycycline post-exposure prophylaxis (doxyPEP) is now included in many clinical guidelines, yet concerns remain regarding antimicrobial resistance (AMR), particularly off-target effects on commensal bacteria in the oropharynx, with intimate behaviours potentially facilitating resistance transmission within sexual networks.

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Publication Details

Journal
The Journal of Infectious Diseases
Published
2025-08-18
DOI
https://doi.org/10.1093/infdis/jiaf439
Citations
1
Primary Topic
Syphilis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
1.16
Controls
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article

Doxycycline Post-exposure Prophylaxis and Off-target Antimicrobial Resistance: Potential Amplification Within Sexual Networks

Peter Davis, Mark Roberts
1 citations
The Journal of Infectious Diseases
Syphilis Diagnosis and Treatment
1.16
article

Doxycycline Post-exposure Prophylaxis and Off-target Antimicrobial Resistance: Potential Amplification Within Sexual Networks

Peter Davis, Mark Roberts
article en
1 citations

Abstract

Doxycycline post-exposure prophylaxis (doxyPEP) is now included in many clinical guidelines, yet concerns remain regarding antimicrobial resistance (AMR), particularly off-target effects on commensal bacteria in the oropharynx, with intimate behaviours potentially facilitating resistance transmission within sexual networks.

The Journal of Infectious Diseases
University of Oxford (GB), Science Oxford (GB), Oxford University Hospitals NHS Trust (GB)
Gender equality
Openalex Percentile: Top 19%
Syphilis Diagnosis and Treatment
1.16
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