Immunological conundrum – A paradoxical reaction in tuberculosis

A paradoxical response is the clinical or radiological worsening of pre-existing tubercular lesions or development of new lesions during anti-tubercular treatment due to host immune reaction. We report to you a 16 year old girl with abdominal tuberculosis presenting to us with large joint swelling and pain, diagnosed to have Poncet’s disease , showed complete resolution of symptoms after re-starting Antitubercular Therapy and a short course of steroids.