Percutaneous Thermal Ablation for Early-Stage Breast Cancer: An Open-Label, Randomized, Phase II Trial to Select the Preferred Technique for Evaluating Thermal Ablation as a Surgical Alternative
This phase II study compared radiofrequency ablation, microwave ablation, and cryoablation for early-stage breast cancer, demonstrating that cryoablation achieved the highest complete ablation rate with no complications, supporting its selection for a phase III trial.
Authors
- Cornelis Verhoef (ORCID: https://orcid.org/0000-0001-9980-8613)
- Belinda J. Schouten
- Gerson M. Struik (ORCID: https://orcid.org/0000-0001-6886-4479)
- Elles M.F. van de Voort (ORCID: https://orcid.org/0000-0003-2392-9763)
- Maura Macco
- Erwin Birnie (ORCID: https://orcid.org/0000-0002-4534-4857)
- Renata Sinke
- Adriaan Moelker (ORCID: https://orcid.org/0000-0002-9503-788X)
- Thijs van Dalen (ORCID: https://orcid.org/0000-0003-0882-9086)
- Sophie M Wooldrik (ORCID: https://orcid.org/0009-0008-7293-5688)
- Glenn Yo
- Suzanne Wilhelmus (ORCID: https://orcid.org/0000-0002-7794-5315)
- Frank Hulsebosch
- T.M.A.L. Klem
Institutions
- University Medical Center Groningen (NL)
- Erasmus MC (NL)
- Sint Franciscus Gasthuis (NL)
- PathoFinder (Netherlands) (NL)
- Erasmus MC Cancer Institute (NL)
- Rotterdam University of Applied Sciences (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Radiology
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1148/radiol.243386
- Citations
- 2
- Primary Topic
- Laser Applications in Dentistry and Medicine
- Type
- article
- Field-Weighted Citation Impact
- 2.72