The role of cystatin C in kidney injury in children and adolescents with type 1 diabetes mellitus: a systematic review

Although individual studies showed some benefit of using serum cystatin C for the prognosis of DKD in pediatric patients with T1D, the meta-analysis of included studies reached no statistical significance. Future clinical studies should focus on the prognostic role of cystatin C (serum and urinary) in identifying kidney injury in pediatric patients with T1D.

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Publication Details

Journal
Brazilian Journal of Nephrology
Published
2025-08-15
DOI
https://doi.org/10.1590/2175-8239-jbn-2024-0236en
Primary Topic
Chronic Kidney Disease and Diabetes
Type
article
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article

The role of cystatin C in kidney injury in children and adolescents with type 1 diabetes mellitus: a systematic review

Athanasios Christoforidis, Assimina Galli‐Τsinopoulou, Paraskevi Panagopoulou, Despoina Tramma et al.
Brazilian Journal of Nephrology
Chronic Kidney Disease and Diabetes
article

The role of cystatin C in kidney injury in children and adolescents with type 1 diabetes mellitus: a systematic review

Athanasios Christoforidis, Assimina Galli‐Τsinopoulou, Paraskevi Panagopoulou, Despoina Tramma, Νikolaos Gkiourtzis, Agni Glava, Maria Moutafi, Panagiota Michou, Anastasia Stoimeni, Georgios Tsigaras, Konstantinos Cheirakis, Aristeidis Christakopoulos
article en

Abstract

Although individual studies showed some benefit of using serum cystatin C for the prognosis of DKD in pediatric patients with T1D, the meta-analysis of included studies reached no statistical significance. Future clinical studies should focus on the prognostic role of cystatin C (serum and urinary) in identifying kidney injury in pediatric patients with T1D.

Brazilian Journal of NephrologyVol. 47(4)
Aristotle University of Thessaloniki (GR), AHEPA University Hospital (GR), Papageorgiou General Hospital (GR), Ippokrateio General Hospital of Thessaloniki (GR)
Openalex Percentile: Top 77%
Chronic Kidney Disease and Diabetes
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The role of cystatin C in kidney injury in children and adolescents with type 1 diabetes mellitus: a systematic review — Athanasios Christoforidis, Assimina Galli‐Τsinopoulou, et al. · Brazilian Journal of Nephrology (2025) | TGRS Research Map | TGRS