Population Structure of <i>Escherichia coli</i> Isolated From the Human Bloodstream, Human and Animal Feces, and the Environment in Northern Tanzania

We found a high diversity of STs among E. coli human bloodstream isolates in Tanzania. Despite this diversity, we observed that an EXPEC9V in development would provide good coverage. Reservoir-attribution studies at finer spatial and temporal scales may better identify transmission networks and reservoirs of ExPECs.

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Publication Details

Journal
The Journal of Infectious Diseases
Published
2025-08-16
DOI
https://doi.org/10.1093/infdis/jiaf437
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
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article

Population Structure of Escherichia coli Isolated From the Human Bloodstream, Human and Animal Feces, and the Environment in Northern Tanzania

Deng B. Madut, Michael J. Maze, John A. Crump, Matthew P. Rubach et al.
3 links
The Journal of Infectious Diseases
Antibiotic Resistance in Bacteria
article

Population Structure of Escherichia coli Isolated From the Human Bloodstream, Human and Animal Feces, and the Environment in Northern Tanzania

Deng B. Madut, Michael J. Maze, John A. Crump, Matthew P. Rubach, Flemming Scheutz, Manuela Carugati, Firdoos Ahmad Gogry, Kajiru Kilonzo, Annette Marandu, Venance P. Maro, Douglas R. Call, Nathaniel H. Kalengo, Bingileki F. Lwezaula, Blandina Theophil Mmbaga, Anne B. Morrissey
article en

Abstract

We found a high diversity of STs among E. coli human bloodstream isolates in Tanzania. Despite this diversity, we observed that an EXPEC9V in development would provide good coverage. Reservoir-attribution studies at finer spatial and temporal scales may better identify transmission networks and reservoirs of ExPECs.

The Journal of Infectious DiseasesVol. 233(1)
Statens Serum Institut (DK), Moshi Co-operative University (TZ), Kilimanjaro Christian Medical Centre (TZ), Duke University Health System (US), St. Francis Referral Hospital (TZ), Washington State University (US), University of Otago (NZ)
Life in Land
Openalex Percentile: Top 83%
Antibiotic Resistance in Bacteria
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Population Structure of <i>Escherichia coli</i> Isolated From the Human Bloodstream, Human and Animal Feces, and the Environment in Northern Tanzania — Deng B. Madut, Michael J. Maze, et al. · The Journal of Infectious Diseases (2025) | TGRS Research Map | TGRS