Diagnostic value of the iron apoptosis-related gene in recurrent miscarriage

The iron apoptosis-related genes such as EGFR, KRAS, SRC, and MDM2 are valuable for the early diagnosis of recurrent miscarriage. They affect the hypoxia of the endometrium during the implantation period through the FoxO signaling pathway, leading to a reduction in the number and volume of microvessels, which in turn causes recurrent miscarriage.

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Publication Details

Journal
Medicine
Published
2025-08-15
DOI
https://doi.org/10.1097/md.0000000000043156
Primary Topic
Prenatal Screening and Diagnostics
Type
article
Field-Weighted Citation Impact
0.00
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Diagnostic value of the iron apoptosis-related gene in recurrent miscarriage

Min Wen, Wenfei Zheng, Hongyuan Song, Wei Xie et al.
1 links
Medicine
Prenatal Screening and Diagnostics
article

Diagnostic value of the iron apoptosis-related gene in recurrent miscarriage

Min Wen, Wenfei Zheng, Hongyuan Song, Wei Xie, Chandana Vayakkali Poochali
article en

Abstract

The iron apoptosis-related genes such as EGFR, KRAS, SRC, and MDM2 are valuable for the early diagnosis of recurrent miscarriage. They affect the hypoxia of the endometrium during the implantation period through the FoxO signaling pathway, leading to a reduction in the number and volume of microvessels, which in turn causes recurrent miscarriage.

MedicineVol. 104(33)
Yichang Central People's Hospital (CN)
Openalex Percentile: Top 70%
Prenatal Screening and Diagnostics
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