An Updated Economic Evaluation of <i> <scp>HLA</scp> ‐B*58:01 </i> Genotype Testing in Gouty Patients for Preventing Severe Allopurinol Hypersensitivity in Thailand

HLA-B*58:01 testing was not cost-effective before allopurinol initiation in Thai patients with gout at the current price of 1,000 THB per test. However, HLA-B*58:01 testing would be cost-effective if only probenecid was the alternative treatment for patients with positive HLA-B*58:01 results. This result would be useful for health authorities, policy decision-makers, and physicians' organizations in providing the recommendation for HLA-B*58:01 testing before initiation of allopurinol.

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Publication Details

Journal
ACR Open Rheumatology
Published
2025-08-01
DOI
https://doi.org/10.1002/acr2.70093
Citations
4
Primary Topic
Urticaria and Related Conditions
Type
article
Field-Weighted Citation Impact
6.67
Controls
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article

An Updated Economic Evaluation of HLA ‐B*58:01 Genotype Testing in Gouty Patients for Preventing Severe Allopurinol Hypersensitivity in Thailand

Nilawan Upakdee, Patapong Towiwat, Wimolsiri Iamsumang, Jirawit Yadee et al.
4 citations
ACR Open Rheumatology
Urticaria and Related Conditions
6.67
article

An Updated Economic Evaluation of HLA ‐B*58:01 Genotype Testing in Gouty Patients for Preventing Severe Allopurinol Hypersensitivity in Thailand

Nilawan Upakdee, Patapong Towiwat, Wimolsiri Iamsumang, Jirawit Yadee, Bodin Butthum, Piyameth Dilokthornsakul, Supinya Dechanont, Apinya Chungcharoenpanich, Boonjing Siripaitoon, Kanon Jatuworapruk, Parawee Chevaisrakul, Ticha Rerkpattanapipat, Worawit Louthrenoo, Suda Vannaprasaht, Suppachai Lawanaskol
article en
4 citations

Abstract

HLA-B*58:01 testing was not cost-effective before allopurinol initiation in Thai patients with gout at the current price of 1,000 THB per test. However, HLA-B*58:01 testing would be cost-effective if only probenecid was the alternative treatment for patients with positive HLA-B*58:01 results. This result would be useful for health authorities, policy decision-makers, and physicians' organizations in providing the recommendation for HLA-B*58:01 testing before initiation of allopurinol.

ACR Open RheumatologyVol. 7(8)
Thammasat University (TH), Prince of Songkla University (TH), Khon Kaen University (TH), Ramathibodi Hospital (TH), Charoenkrung Pracharak Hospital (TH), Chiang Mai University (TH), Naresuan University (TH)
Openalex Percentile: Top 3%
Urticaria and Related Conditions
6.67
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