The Relationship of Alzheimer's Disease and Related Dementias Blood‐Based Biomarkers and Informant‐Reported Neuropsychiatric Symptoms Differs by Informant Type in Older Adults Without Dementia
Informant type modified the association between AD/ADRD BBMs and NPS, with stronger associations observed when symptoms were reported by child informants compared to spouse informants. These findings have important implications for earlier detection of individuals with AD/ADRD pathologies.
Authors
- Suzanne Craft (ORCID: https://orcid.org/0000-0003-0591-8657)
- James R. Bateman
- Marc D. Rudolph (ORCID: https://orcid.org/0000-0001-7046-1169)
- Samuel N. Lockhart (ORCID: https://orcid.org/0000-0002-0893-5420)
- Michelle M. Mielke (ORCID: https://orcid.org/0000-0001-7177-1185)
- Julia R. Bacci (ORCID: https://orcid.org/0009-0005-7408-0984)
Institutions
- Atrium Health Wake Forest Baptist (US)
- Wake Forest University (US)
Publication Details
- Journal
- International Journal of Geriatric Psychiatry
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1002/gps.70140
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- Astrophysics Division