Cuproptosis in atrazine-induced hepatotoxicity: ATOX1 as a therapeutic target for lycopene-mediated protection

Overall, it was determined that ATOX1-mediated cuproptosis is involved in ATR-induced hepatotoxicity and the therapeutic effects of LYC. The findings enrich the understanding of the pathogenesis of ATR-induced liver toxicity and provide data to support further cuproptosis studies.

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Publication Details

Journal
Journal of Advanced Research
Published
2025-08-01
DOI
https://doi.org/10.1016/j.jare.2025.08.024
Citations
3
Primary Topic
Vitamin C and Antioxidants Research
Type
article
Field-Weighted Citation Impact
3.36
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article

Cuproptosis in atrazine-induced hepatotoxicity: ATOX1 as a therapeutic target for lycopene-mediated protection

Tiantian Zhang, Nan Li, Weihong Lu, Yu-Qian Zhang et al.
3 citations
Journal of Advanced Research
Vitamin C and Antioxidants Research
3.36
article

Cuproptosis in atrazine-induced hepatotoxicity: ATOX1 as a therapeutic target for lycopene-mediated protection

Tiantian Zhang, Nan Li, Weihong Lu, Yu-Qian Zhang, Zhao Yang, Yingying Liu, Jin‐Long Li, Xin Yao
article en
3 citations

Abstract

Overall, it was determined that ATOX1-mediated cuproptosis is involved in ATR-induced hepatotoxicity and the therapeutic effects of LYC. The findings enrich the understanding of the pathogenesis of ATR-induced liver toxicity and provide data to support further cuproptosis studies.

Journal of Advanced Research
Northeast Agricultural University (CN)
Zero hunger
Openalex Percentile: Top 8%
Vitamin C and Antioxidants Research
3.36
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