Chondromyxoid Fibroma of the Nasal Cavity: A Benign Tumor in a Rare Head and Neck Location

Chondromyxoid fibroma (CMF) is a rare benign bone tumor that infrequently involves the craniofacial skeleton. Its diagnosis can be challenging due to overlapping imaging features with other lesions. We report a case of a 72-year-old female in whom a right posterior nasal mass was incidentally identified on MRI. The patient was asymptomatic, and endoscopic examination revealed a spherical lesion near the posterior inferior turbinate. CMF was confirmed on CT imaging and histopathologic analysis. This case highlights an unusual presentation of CMF in the posterior nasal cavity. It also emphasizes the importance of a thorough workup, including imaging and histopathologic data, as CMF in the head and neck region often mimics more aggressive neoplasms, posing diagnostic challenges.

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Publication Details

Journal
Cureus
Published
2025-08-19
DOI
https://doi.org/10.7759/cureus.90488
Primary Topic
Bone Tumor Diagnosis and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Chondromyxoid Fibroma of the Nasal Cavity: A Benign Tumor in a Rare Head and Neck Location

Michael J. Ferguson, Chelsea Onyeji, Alycia Boutrand
Cureus
Bone Tumor Diagnosis and Treatments
article

Chondromyxoid Fibroma of the Nasal Cavity: A Benign Tumor in a Rare Head and Neck Location

Michael J. Ferguson, Chelsea Onyeji, Alycia Boutrand
article en

Abstract

Chondromyxoid fibroma (CMF) is a rare benign bone tumor that infrequently involves the craniofacial skeleton. Its diagnosis can be challenging due to overlapping imaging features with other lesions. We report a case of a 72-year-old female in whom a right posterior nasal mass was incidentally identified on MRI. The patient was asymptomatic, and endoscopic examination revealed a spherical lesion near the posterior inferior turbinate. CMF was confirmed on CT imaging and histopathologic analysis. This case highlights an unusual presentation of CMF in the posterior nasal cavity. It also emphasizes the importance of a thorough workup, including imaging and histopathologic data, as CMF in the head and neck region often mimics more aggressive neoplasms, posing diagnostic challenges.

CureusVol. 17(8)
University of North Carolina at Chapel Hill (US), WakeMed (US)
Openalex Percentile: Top 67%
Bone Tumor Diagnosis and Treatments
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