68Ga-FAPI-04 Versus 18F-FDG PET/CT in a Case of Xanthogranulomatous Cholecystitis

Xanthogranulomatous cholecystitis (XGC) is an uncommon inflammatory disease of the gallbladder. We report a case of XGC with elevated activity of 18 F-FDG and 68 Ga-FAPI (fibroblast activating protein inhibitor), which mimics malignancy. Our case suggests that XGS should be considered in the differential diagnosis of cancer-like gallbladder lesions with increased 68 Ga-FAPI uptake.

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Publication Details

Journal
Clinical Nuclear Medicine
Published
2025-08-18
DOI
https://doi.org/10.1097/rlu.0000000000005984
Citations
1
Primary Topic
Peptidase Inhibition and Analysis
Type
article
Field-Weighted Citation Impact
1.05
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article

68Ga-FAPI-04 Versus 18F-FDG PET/CT in a Case of Xanthogranulomatous Cholecystitis

Yang Xie, Yue Chen, Xinyi Lin
1 citations
Clinical Nuclear Medicine
Peptidase Inhibition and Analysis
1.05
article

68Ga-FAPI-04 Versus 18F-FDG PET/CT in a Case of Xanthogranulomatous Cholecystitis

Yang Xie, Yue Chen, Xinyi Lin
article en
1 citations

Abstract

Xanthogranulomatous cholecystitis (XGC) is an uncommon inflammatory disease of the gallbladder. We report a case of XGC with elevated activity of 18 F-FDG and 68 Ga-FAPI (fibroblast activating protein inhibitor), which mimics malignancy. Our case suggests that XGS should be considered in the differential diagnosis of cancer-like gallbladder lesions with increased 68 Ga-FAPI uptake.

Clinical Nuclear MedicineVol. 50(12)
Target (United States) (US), Southwest Medical University (CN), Affiliated Hospital of Southwest Medical University (CN)
Openalex Percentile: Top 19%
Peptidase Inhibition and Analysis
1.05
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