Added value of cell‐free <scp>DNA</scp> over clinical and ultrasound information for diagnosing ovarian cancer
Although statistically significant, cfDNA-based biomarker scores have limited clinical utility in addition to established clinical and ultrasound-based ADNEX predictors for discriminating between benign and malignant ovarian masses. © 2025 International Society of Ultrasound in Obstetrics and Gynecology.
Authors
- D. Timmerman (ORCID: https://orcid.org/0000-0002-3707-6645)
- Thaïs Baert (ORCID: https://orcid.org/0000-0001-7207-1519)
- A. C. Testa (ORCID: https://orcid.org/0000-0003-2217-8726)
- D. Fischerová (ORCID: https://orcid.org/0000-0002-7224-3218)
- F. Moro (ORCID: https://orcid.org/0000-0002-5070-7245)
- Tom Venken (ORCID: https://orcid.org/0000-0003-0773-1810)
- Pieter Busschaert
- C. Landolfo (ORCID: https://orcid.org/0000-0001-9808-7957)
- Adriaan Vanderstichele (ORCID: https://orcid.org/0000-0002-3984-2948)
- An Coosemans (ORCID: https://orcid.org/0000-0002-7321-4339)
- Joris Robert Vermeesch (ORCID: https://orcid.org/0000-0002-3071-1191)
- Diether Lambrechts (ORCID: https://orcid.org/0000-0002-3429-302X)
- Jolien Ceusters (ORCID: https://orcid.org/0000-0001-5422-5668)
- Wouter Froyman (ORCID: https://orcid.org/0000-0002-1398-9124)
- Ben Van Calster (ORCID: https://orcid.org/0000-0003-1613-7450)
Institutions
- Università Cattolica del Sacro Cuore (IT)
- Charles University (CZ)
- Rega Institute for Medical Research (BE)
- Leiden University Medical Center (NL)
- Agostino Gemelli University Polyclinic (IT)
- VIB-KU Leuven Center for Cancer Biology (BE)
- Center for Human Genetics (US)
- Zero to Three (US)
- Doctors of the World (US)
- Queen Charlotte's and Chelsea Hospital (GB)
- AZ Delta (BE)
- General University Hospital in Prague (CZ)
- Imperial College London (GB)
- KU Leuven (BE)
Publication Details
- Journal
- Ultrasound in Obstetrics and Gynecology
- Published
- 2025-08-19
- DOI
- https://doi.org/10.1002/uog.29314
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fonds Wetenschappelijk Onderzoek
- KU Leuven
- Kom op tegen Kanker