Pharmacokinetics, Safety, Tolerability and Antiviral Activity of Switching to Oral Rilpivirine in Combination With Other Antiretroviral Therapy in Virologically Suppressed Children Living With HIV-1 Infection: Forty-eight-week Results From the Phase
Rilpivirine in combination with background ART was well-tolerated and maintained virologic suppression from baseline through week 48 in the studied population of children living with HIV-1. Rilpivirine exposure was within the target range for all doses.
Authors
- Simon Vanveggel
- Francis Ssali
- Minaka Shibuya
- Ken Kurosawa (ORCID: https://orcid.org/0000-0003-3496-883X)
- Johan Lombaard (ORCID: https://orcid.org/0000-0002-3229-7182)
- Sandy Van Hemelryck (ORCID: https://orcid.org/0000-0002-0103-8225)
- Clàudia Fortuny (ORCID: https://orcid.org/0000-0001-7182-5745)
- Supattra Rungmaitree (ORCID: https://orcid.org/0000-0001-9439-9152)
- Erika Van Landuyt
- Rodica Van Solingen‐Ristea (ORCID: https://orcid.org/0000-0003-2301-7430)
- Alberto Russu (ORCID: https://orcid.org/0000-0003-2095-4365)
- Margarida Tavares (ORCID: https://orcid.org/0000-0003-4518-2197)
- Veerle Van Eygen (ORCID: https://orcid.org/0000-0001-8804-1613)
- Visal Moolasart (ORCID: https://orcid.org/0000-0002-1151-4790)
- Raffaele Badolato (ORCID: https://orcid.org/0000-0001-7375-5410)
- Alfredo Guarino (ORCID: https://orcid.org/0000-0003-0199-0336)
- Stefania Bernardi (ORCID: https://orcid.org/0000-0001-5672-0881)
- Linda Aurpibul (ORCID: https://orcid.org/0000-0003-0246-8187)
Institutions
- Hospital Sant Joan de Déu Barcelona (ES)
- Ministry of Public Health (TH)
- Siriraj Hospital (TH)
- Mahidol University (TH)
- Hospital de São João (PT)
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT)
- Johnson Controls (Japan) (JP)
- Bamrasnaradura Infectious Diseases Institute (TH)
- Federico II University Hospital (IT)
- Bambino Gesù Children's Hospital (IT)
- Johnson & Johnson (Italy) (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Joint Clinical Research Centre (UG)
- University of Brescia (IT)
Publication Details
- Journal
- The Pediatric Infectious Disease Journal
- Published
- 2025-08-13
- DOI
- https://doi.org/10.1097/inf.0000000000004943
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Janssen Research and Development