Emergence of Antiviral Drug Resistance in Congenital Cytomegalovirus Infection During Treatment: An Updated Review of Literature and Case Report
Limited data exist on the prevalence and clinical consequences of drug resistance in cCMV. The case described here depicts the surveillance of viral infection and the emergence of drug resistance, which was managed by administering combination antiviral therapy. It emphasizes the need for further research into the management of severe cCMV infections and the need for monitoring antiviral drug resistance to implement adapted treatment strategies.
Authors
- Piet Maes (ORCID: https://orcid.org/0000-0002-4571-5232)
- Giang Ho
- Graciela Andreï (ORCID: https://orcid.org/0000-0003-2609-4896)
- Sarah Dorval (ORCID: https://orcid.org/0000-0003-0746-2737)
- Sarah Gillemot
- Robert Snoeck (ORCID: https://orcid.org/0000-0002-7586-5434)
- Fien Horsten (ORCID: https://orcid.org/0000-0001-7633-3731)
Institutions
- Rega Institute for Medical Research (BE)
- Centre Hospitalier Chrétien (BE)
- Clinique Saint-Joseph (BE)
- Pediatric Infectious Diseases Society (US)
- KU Leuven (BE)
Publication Details
- Journal
- The Pediatric Infectious Disease Journal
- Published
- 2025-08-15
- DOI
- https://doi.org/10.1097/inf.0000000000004948
- Primary Topic
- Cytomegalovirus and herpesvirus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00