Both Corticosteroids and Intravenous Immunoglobulin Protect From Aneurysms in Children With Multisystem Inflammatory Syndrome: A Multicenter Ambispective Study
Corticosteroids, IVIG and their combination appear to be protective against aneurysms in children with MIS-C compared with no immunomodulatory treatment. Although the 3 therapies showed no significant differences when compared with each other, only the combination significantly reduced the risk. Corticosteroids may still be a useful option when IVIG is limited.
Authors
- María Lucia Mesa-Rubio
- Leszek Szenborn (ORCID: https://orcid.org/0000-0001-6574-8229)
- Carlos Grasa (ORCID: https://orcid.org/0000-0002-9323-2024)
- Sara Domínguez‐Rodríguez (ORCID: https://orcid.org/0000-0003-3747-9265)
- Cinta Moraleda (ORCID: https://orcid.org/0000-0002-8335-903X)
- Victòria Fumadó (ORCID: https://orcid.org/0000-0002-3287-252X)
- A. Martínez (ORCID: https://orcid.org/0000-0003-4437-4963)
- Antoni Soriano‐Arandes (ORCID: https://orcid.org/0000-0001-9613-7228)
- Fernando Paredes-Carmona (ORCID: https://orcid.org/0000-0002-2247-0930)
- Cristina Epalza (ORCID: https://orcid.org/0000-0002-6929-4903)
- Magdalena Okarska‐Napierała (ORCID: https://orcid.org/0000-0003-1668-6302)
- Kamila Maria Ludwikowska (ORCID: https://orcid.org/0000-0002-4128-3401)
- Alfredo Tagarro (ORCID: https://orcid.org/0000-0003-2860-3455)
- Andrea Ramírez Varela (ORCID: https://orcid.org/0000-0003-2685-9617)
- Miron B. Kursa (ORCID: https://orcid.org/0000-0001-7672-648X)
- Ernest Kuchar (ORCID: https://orcid.org/0000-0002-7883-2427)
- Irati Gastesi (ORCID: https://orcid.org/0009-0006-8566-8430)
- María Isabel Iglesias‐Bouzas
- Ana Roche-Gómez
- Natalia Kulboka
Institutions
- Hospital Sant Joan de Déu Barcelona (ES)
- Universidad de Los Andes (CO)
- Medical University of Warsaw (PL)
- Hospital Universitario La Paz (ES)
- Instituto de Salud Carlos III (ES)
- Hospital Universitari Arnau de Vilanova (ES)
- Wroclaw Medical University (PL)
- Research Institute Hospital 12 de Octubre (ES)
- Consorci Sanitari de Terrassa (ES)
- Hospital Universitario 12 De Octubre (ES)
- Hospital La Paz Institute for Health Research (ES)
- Centre for Biomedical Network Research on Rare Diseases (ES)
- Vall d'Hebron Hospital Universitari (ES)
- Hospital del Niño (PA)
- Hospital Universitario Infanta Sofía (ES)
- University of Warsaw (PL)
- Universidad Europea de Madrid (ES)
Publication Details
- Journal
- The Pediatric Infectious Disease Journal
- Published
- 2025-08-12
- DOI
- https://doi.org/10.1097/inf.0000000000004922
- Citations
- 1
- Primary Topic
- Kawasaki Disease and Coronary Complications
- Type
- article
- Field-Weighted Citation Impact
- 2.01