Assessment of a Semi-solid Extrusion Based Compounding System Solution for Personalized Ondansetron Dosage Forms Combined with Raman Spectroscopy Analysis
In conclusion, the CSS technology, validated through pharmacopoeia tests, HPLC, and RS, effectively produces high-quality, personalized Ondansetron tablets. The study demonstrates the feasibility of using SSE and RS-based quality control for individualized pediatric drug formulations.
Authors
- Timo Laaksonen (ORCID: https://orcid.org/0000-0002-6699-3004)
- Tapani Viitala (ORCID: https://orcid.org/0000-0001-9074-9450)
- Soumya Verma
- Jacopo Zini (ORCID: https://orcid.org/0000-0001-8021-3679)
- Sari Airaksinen
- Niklas Sandler Topelius
- Julius Lahtinen (ORCID: https://orcid.org/0009-0006-5451-7963)
- Niko Hassinen
- Mahsa Bahman
Institutions
- Åbo Akademi University (FI)
- University of Helsinki (FI)
Publication Details
- Journal
- Pharmaceutical Research
- Published
- 2025-08-19
- DOI
- https://doi.org/10.1007/s11095-025-03911-6
- Primary Topic
- 3D Printing in Biomedical Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Åbo Akademi