Large Language Models Use in Dry Eye Disease: Perplexity AI versus ChatGPT4

Perplexity AI and ChatGPT performed similarly for patient-related queries on DED and could have a role in patient education. These LLMs could have a role in DED clinics for patient counseling but require supervision. The LLMs are not ready to generate dry-eye research ideas or perform literature searches for DED.

Authors

Institutions

Publication Details

Journal
Seminars in Ophthalmology
Published
2025-08-19
DOI
https://doi.org/10.1080/08820538.2025.2547077
Citations
2
Primary Topic
Ocular Surface and Contact Lens
Type
article
Field-Weighted Citation Impact
3.76

Funders

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article

Large Language Models Use in Dry Eye Disease: Perplexity AI versus ChatGPT4

Sayan Basu, Swati Singh, Stephanie L. Watson, Sowmya V Kothandan
2 citations
Seminars in Ophthalmology
Ocular Surface and Contact Lens
3.76
article

Large Language Models Use in Dry Eye Disease: Perplexity AI versus ChatGPT4

Sayan Basu, Swati Singh, Stephanie L. Watson, Sowmya V Kothandan
article en
2 citations

Abstract

Perplexity AI and ChatGPT performed similarly for patient-related queries on DED and could have a role in patient education. These LLMs could have a role in DED clinics for patient counseling but require supervision. The LLMs are not ready to generate dry-eye research ideas or perform literature searches for DED.

Seminars in OphthalmologyVol. 41(3)
The University of Sydney (AU), L V Prasad Eye Institute (IN)
Hyderabad Eye Research Foundation
Openalex Percentile: Top 7%
Ocular Surface and Contact Lens
3.76
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