Clinicopathological Features and Pathogenesis of Thymoma Complicated with Alopecia Areata: A Multicenter, Matched Case Analysis

We hypothesize that the pathogenesis of thymoma with AA differs from that of thymoma with MG, though there may be a correlation. The etiology of thymoma with AA may be attributed to abnormal autoimmune CD8<sup>+</sup> T lymphocytes produced by the thymoma, which can also lead to other cytotoxic T-cell-mediated autoimmune diseases.

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Publication Details

Journal
Cancers
Published
2025-08-16
DOI
https://doi.org/10.3390/cancers17162672
Primary Topic
Myasthenia Gravis and Thymoma
Type
article
Field-Weighted Citation Impact
0.00

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article

Clinicopathological Features and Pathogenesis of Thymoma Complicated with Alopecia Areata: A Multicenter, Matched Case Analysis

Yeye Chen, Xintao Yu, Xiayao Diao, Xuehan Gao et al.
Cancers
Myasthenia Gravis and Thymoma
article

Clinicopathological Features and Pathogenesis of Thymoma Complicated with Alopecia Areata: A Multicenter, Matched Case Analysis

Yeye Chen, Xintao Yu, Xiayao Diao, Xuehan Gao, Chao Guo, Jian Cui, Ye Zhang, Xin Du, Shanqing Li, Lei Yu, Chao Gao, Cheng Huang
article en

Abstract

We hypothesize that the pathogenesis of thymoma with AA differs from that of thymoma with MG, though there may be a correlation. The etiology of thymoma with AA may be attributed to abnormal autoimmune CD8<sup>+</sup> T lymphocytes produced by the thymoma, which can also lead to other cytotoxic T-cell-mediated autoimmune diseases.

CancersVol. 17(16)
Beijing Tongren Hospital (CN), Capital Medical University (CN), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN)
Peking Union Medical College Hospital, Beijing Association for Science and Technology
Good health and well-being
Openalex Percentile: Top 69%
Myasthenia Gravis and Thymoma
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