Multi-Omics Profiling of the 42-Day Infant Gut as a Pilot Predictor of Atopic Dermatitis at One Year: A Birth Cohort Study in China
Multi-omics profiling of the infant gut at 42 days identified microbial and metabolic features associated with later AD development. These findings support the gut-skin axis and suggest potential early-life biomarkers for predicting AD risk and informing targeted prevention strategies.
Authors
- Dongsheng Yu (ORCID: https://orcid.org/0000-0003-4222-3985)
- Chunping Shen (ORCID: https://orcid.org/0000-0002-6275-8541)
- Xu Li (ORCID: https://orcid.org/0009-0005-9184-5985)
- Lin Ma (ORCID: https://orcid.org/0000-0001-7625-9842)
- Mutong Zhao (ORCID: https://orcid.org/0000-0002-1885-4579)
- Shan Wang (ORCID: https://orcid.org/0000-0003-2177-5318)
- Ying Liu
- Jing Tian (ORCID: https://orcid.org/0000-0002-7399-0960)
- Lili Ma (ORCID: https://orcid.org/0000-0002-1197-9299)
- Yan Li (ORCID: https://orcid.org/0000-0002-3209-4465)
- Xiuhua Ma (ORCID: https://orcid.org/0000-0002-3520-085X)
- Liang Yuan (ORCID: https://orcid.org/0000-0003-1734-9869)
Institutions
- Capital Medical University (CN)
- Beijing Children’s Hospital (CN)
- Shandong Provincial QianFoShan Hospital (CN)
- Shaoxing People's Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-08-01
- DOI
- https://doi.org/10.2147/jir.s534551
- Citations
- 2
- Primary Topic
- Dermatology and Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 4.01
Funders
- National Natural Science Foundation of China