Vocal Markers of Schizophrenia: Assessing the Generalizability of Machine Learning Models and Their Clinical Applicability

Overall, the cross-linguistic generalizability of vocal markers of schizophrenia is limited. We argue that more emphasis should be placed on collecting large open cross-linguistic datasets to systematically test the generalizability of voice-based ML models, and on identifying more precise mechanisms of how the clinical features of schizophrenia are expressed in language and voice, and how different languages vary in that expression.

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Publication Details

Journal
Schizophrenia Bulletin
Published
2025-08-18
DOI
https://doi.org/10.1093/schbul/sbaf124
Citations
2
Primary Topic
Music and Audio Processing
Type
article
Field-Weighted Citation Impact
2.97
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article

Vocal Markers of Schizophrenia: Assessing the Generalizability of Machine Learning Models and Their Clinical Applicability

Arndis Simonsen, Jessica Mary Lin, Astrid Rybner, Katja Koelkebeck et al.
2 citations
Schizophrenia Bulletin
Music and Audio Processing
2.97
article

Vocal Markers of Schizophrenia: Assessing the Generalizability of Machine Learning Models and Their Clinical Applicability

Arndis Simonsen, Jessica Mary Lin, Astrid Rybner, Katja Koelkebeck, Vibeke Bliksted, Riccardo Fusaroli, Yuan Zhou, Alberto Parola, Emil Trenckner Jessen, Marie Damsgaard Mortensen, Konstantinos Sechidis, Stine Nyhus Larsen, Huiling Wang
article en
2 citations

Abstract

Overall, the cross-linguistic generalizability of vocal markers of schizophrenia is limited. We argue that more emphasis should be placed on collecting large open cross-linguistic datasets to systematically test the generalizability of voice-based ML models, and on identifying more precise mechanisms of how the clinical features of schizophrenia are expressed in language and voice, and how different languages vary in that expression.

Schizophrenia Bulletin
Novartis (Switzerland) (CH), Center for Applied Linguistics (US), University of Southern Denmark (DK), Aarhus University (DK), Odense University Hospital (DK), Aarhus University Hospital (DK), Wuhan University (CN), State and University Library (DK), Pennsylvania Academic Library Consortium (US), Renmin Hospital of Wuhan University (CN), Institute of Physics (CN), University of Chinese Academy of Sciences (CN), Bethel University (US)
Openalex Percentile: Top 8%
Music and Audio Processing
2.97
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