Mechanistic <i>in vivo</i> studies of secondary skin-to-skin peanut allergen transfer to determine the impact of hand washing in reducing the risk of cutaneous sensitization
We demonstrate the rapid contamination of hands with allergenic peanut protein and the potential for skin-to-skin transfer. Hand hygiene prevented allergen transmission by up to 90%. Soaps based on nonionic surfactants were more robust to external factors than classical anionic soaps, and this may be particularly important for infants with AD.
Authors
- Preeti Khurana (ORCID: https://orcid.org/0000-0002-0252-9819)
- Stuart Allen Jones (ORCID: https://orcid.org/0000-0001-5078-0250)
- Martina C. Meinke (ORCID: https://orcid.org/0000-0002-3937-9906)
- Carsten Flohr (ORCID: https://orcid.org/0000-0003-4884-6286)
- Loris Busch (ORCID: https://orcid.org/0000-0002-2671-2028)
- Silke B. Lohan (ORCID: https://orcid.org/0000-0001-8156-0074)
- Anna Lena Klein (ORCID: https://orcid.org/0000-0002-8169-2541)
- Sumayah Abdul-Jabbar
- Faiza Benaouda (ORCID: https://orcid.org/0000-0003-4673-4336)
- Victor Hugo Pacagnelli Infante (ORCID: https://orcid.org/0000-0001-7151-5755)
- Alexandra F. Santos (ORCID: https://orcid.org/0000-0002-7805-1436)
- Natalija Novak (ORCID: https://orcid.org/0000-0002-2458-3867)
- Constanze Baber
Institutions
- St Thomas' Hospital (GB)
- King's College London (GB)
- Guy's and St Thomas' NHS Foundation Trust (GB)
- University Hospital Bonn (DE)
- Humboldt-Universität zu Berlin (DE)
- Evelina London Children's Healthcare (GB)
- St Peter's Hospital (US)
Publication Details
- Journal
- British Journal of Dermatology
- Published
- 2025-08-07
- DOI
- https://doi.org/10.1093/bjd/ljaf214
- Citations
- 1
- Primary Topic
- Food Allergy and Anaphylaxis Research
- Type
- article
- Field-Weighted Citation Impact
- 1.62
Funders
- Joint Programming Initiative A healthy diet for a healthy life
- European Commission
- Bundesministerium für Bildung und Forschung