Gestational diabetes mellitus: the role of IGF-1 and leptin in cord blood
Elevated IGF-1 and leptin levels were associated with fetal macrosomia. IGF-1 turned out to be significantly different between LGA and non-LGA newborns of diabetic mothers, even though there were only 6 LGA cases. Metabolic differences between GDM and C infants may not be detectable with tight control of diabetes during pregnancy.
Authors
- Roland Hentschel (ORCID: https://orcid.org/0000-0003-0411-4067)
- Marc Thill (ORCID: https://orcid.org/0000-0002-8800-8044)
- Jochen Seufert (ORCID: https://orcid.org/0000-0001-5654-7310)
- Jeffrey G. Trost (ORCID: https://orcid.org/0000-0002-2593-4497)
- Mirjam Kunze (ORCID: https://orcid.org/0000-0003-4064-5930)
- Karl Otfried Schwab
- Alexandra Krause
Institutions
- University of Freiburg (DE)
- University Medical Center Freiburg (DE)
Publication Details
- Journal
- Journal of Perinatal Medicine
- Published
- 2025-08-19
- DOI
- https://doi.org/10.1515/jpm-2024-0379
- Primary Topic
- Gestational Diabetes Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00