Social Isolation Induces Sex‐Differentiated Sensory‐Emotional Pain Responses and Oxytocinergic Receptors Alterations in Mice
This article shows that social isolation enhances pain perception and oxytocinergic neurotransmission, especially in female mice. This understanding of how pain affects different sexes may contribute to developing a sex-specific new therapeutic target to assist individuals living with pain.
Authors
- Ricardo Luiz Nunes‐de‐Souza (ORCID: https://orcid.org/0000-0003-2498-991X)
- Carlos César Crestani (ORCID: https://orcid.org/0000-0002-1942-858X)
- Lucas Canto‐de‐Souza (ORCID: https://orcid.org/0000-0002-8203-4903)
- Azair Canto‐de‐Souza (ORCID: https://orcid.org/0000-0002-0828-7670)
- Daniela Baptista‐de‐Souza (ORCID: https://orcid.org/0000-0002-3252-3928)
- Miguel Oliveira (ORCID: https://orcid.org/0000-0002-6786-1900)
- Ana Claudia Braga‐Dias
- Silvia Jimena Cardenas Otero
Institutions
- Department of Physiological Sciences (RU)
- Centro Universitário de Araraquara (BR)
- Universidade Estadual Paulista (Unesp) (BR)
Publication Details
- Journal
- European Journal of Pain
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1002/ejp.70106
- Citations
- 1
- Primary Topic
- Neuroendocrine regulation and behavior
- Type
- article
- Field-Weighted Citation Impact
- 2.44