Non-invasive fluorescence sensing reveals changes in intestinal barrier function and gastric emptying rate in a first-in-human study of Crohn’s disease
The clinical study reported in this article was registered with ClinicalTrials.gov prior to enrolment of the first participant. https://clinicaltrials.gov/study/NCT03434639 and Registration number: NCT03434639.
Authors
- Nilanjan Mandal (ORCID: https://orcid.org/0000-0001-9777-1503)
- Jiacheng Xu (ORCID: https://orcid.org/0000-0003-4753-0634)
- Sharmili Balarajah (ORCID: https://orcid.org/0000-0003-0229-8528)
- Lynn Maslen (ORCID: https://orcid.org/0000-0002-6657-3296)
- Karl King Yong (ORCID: https://orcid.org/0000-0002-1586-1255)
- Elena Monfort Sánchez
- James Avery (ORCID: https://orcid.org/0000-0002-4015-1802)
- James Leslie Alexander (ORCID: https://orcid.org/0000-0001-8542-327X)
- Hutan Ashrafian (ORCID: https://orcid.org/0000-0003-1668-0672)
- Ash Salam
- María Gómez‐Romero (ORCID: https://orcid.org/0000-0003-4884-7721)
- Ara Wardkes Darzi (ORCID: https://orcid.org/0000-0001-7815-7989)
- Nick Powell (ORCID: https://orcid.org/0000-0003-3231-6950)
- Jonathan Gan (ORCID: https://orcid.org/0000-0001-7410-1902)
- Jonathan M. Hoare (ORCID: https://orcid.org/0009-0001-3856-9206)
- Elena Chekmeneva (ORCID: https://orcid.org/0000-0003-1807-2398)
- Robert Perry (ORCID: https://orcid.org/0000-0003-0149-6530)
- Qian Chen (ORCID: https://orcid.org/0000-0001-6516-8275)
- Zixin Wang (ORCID: https://orcid.org/0000-0002-1158-2304)
- Alex J. Thompson (ORCID: https://orcid.org/0000-0002-2485-1550)
- Arjun Agarwal
- Pratik Ramkumar
- Emmanuel Oluwatunmise
Institutions
- Imperial College Healthcare NHS Trust (GB)
- St. Mark's Hospital (US)
- St Mary's Hospital (GB)
- St Mark's Hospital (GB)
- Imperial College London (GB)
Publication Details
- Journal
- Therapeutic Advances in Gastroenterology
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1177/17562848251361634
- Citations
- 3
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 5.45