Effectiveness of ChAdOx1 nCoV-19 (Vaxzevria) primary series vaccine against SARS-CoV-2 beta and delta variants: a nationwide study
The ChAdOx1 nCoV-19 vaccine provided substantial protection against infection and strong protection against severe outcomes during periods dominated by the Beta and Delta variants, although protection against infection waned within the first few months following the primary series.
Authors
- Mohamed H. Al‐Thani (ORCID: https://orcid.org/0000-0003-2501-6941)
- Laith Jamal Abu-Raddad (ORCID: https://orcid.org/0000-0003-0790-0506)
- Gheyath K. Nasrallah (ORCID: https://orcid.org/0000-0001-9252-1038)
- Hadi Mohamad Yassine (ORCID: https://orcid.org/0000-0001-7592-2788)
- Hiam S. Chemaitelly (ORCID: https://orcid.org/0000-0002-8756-6968)
- Abdullatif Al‐Khal (ORCID: https://orcid.org/0000-0003-3737-8253)
- Roberto Bertollini (ORCID: https://orcid.org/0000-0003-3606-9344)
- Anvar Hassan Kaleeckal (ORCID: https://orcid.org/0000-0002-9650-4750)
- Andrew Jeremijenko
- Riyazuddin Mohammad Shaik (ORCID: https://orcid.org/0009-0005-0550-7323)
- Zaina Al Kanaani (ORCID: https://orcid.org/0000-0003-2297-4255)
- Adeel A. Butt (ORCID: https://orcid.org/0000-0002-1118-1826)
- Ali Nizar Latif (ORCID: https://orcid.org/0000-0001-9011-4391)
- Hanan F. Abdul Rahim (ORCID: https://orcid.org/0000-0002-3719-5142)
- Houssein H. Ayoub (ORCID: https://orcid.org/0000-0003-2512-6657)
- Patrick Tang (ORCID: https://orcid.org/0000-0003-1583-5484)
- Peter Coyle (ORCID: https://orcid.org/0000-0002-0819-6103)
- Mohamed Ghaith Al‐Kuwari (ORCID: https://orcid.org/0000-0002-9666-0622)
- Mohammad R. Hasan (ORCID: https://orcid.org/0000-0003-2641-5741)
- Einas Al‐Kuwari
- Hamad Eid Al-Romaihi
- Asmaa A. Al Thani (ORCID: https://orcid.org/0000-0003-2715-3712)
Institutions
- Queen's University Belfast (GB)
- University of British Columbia (CA)
- Cornell University (US)
- Ministry of Public Health (QA)
- Primary Health Care (QA)
- Hamad bin Khalifa University (QA)
- Weill Cornell Medical College in Qatar (QA)
- Hamad Medical Corporation (QA)
- Qatar University (QA)
- McMaster University (CA)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-08-17
- DOI
- https://doi.org/10.1186/s12879-025-11410-7
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- L'Oreal USA
- Hamad Medical Corporation
- Sidra Medicine
- Qatar University
- Weill Cornell Medical College
- Weill Cornell Medicine - Qatar
- Qatar National Library