Clinical significance of focal segmental glomerulosclerosis subclassification in IgA nephropathy
Our study validated the clinical value of S subclassification in IgAN in an Asian population. Patients with NOS+Adh+ lesions have more severe proteinuria and renal function damage. Their overall renal prognosis is significantly worse; however, they can benefit from a treatment strategy that combines renin-angiotensin system inhibitors with immunosuppressants. In addition, controlling SBP to below 130 mmHg seems to be an appropriate range.
Authors
- Huijuan Mao (ORCID: https://orcid.org/0000-0001-7410-1486)
- Tiekun Li
- Fang Lu (ORCID: https://orcid.org/0000-0002-8927-2437)
- Yanggang Yuan (ORCID: https://orcid.org/0000-0003-2764-9486)
- Hua Shu
- Changying Xing
- Qing Li (ORCID: https://orcid.org/0000-0002-6019-4703)
- Lin Wu (ORCID: https://orcid.org/0000-0001-9358-0814)
- Shuisheng Hou (ORCID: https://orcid.org/0000-0001-8016-8863)
- Yan Wu
- Suyan Duan (ORCID: https://orcid.org/0009-0003-6529-3801)
- Bo Zhang (ORCID: https://orcid.org/0009-0000-7452-5510)
- Ying Pan
- Chang Liu (ORCID: https://orcid.org/0000-0003-0650-1773)
Institutions
- Kingmed Diagnostics (CN)
- Jiangsu Province Hospital (CN)
- The Fifth People’s Hospital of Suzhou (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Nephrology Dialysis Transplantation
- Published
- 2025-08-15
- DOI
- https://doi.org/10.1093/ndt/gfaf162
- Citations
- 1
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 1.43