<i>Chlamydia trachomatis</i> and <i>Neisseria gonorrhoeae</i> bacterial loads in men who have sex with men on pre-exposure prophylaxis: a cross-sectional study
In contrast to prior research, we found similar bacterial burdens in anorectal MSM samples with single CT/NG versus coinfection. Further research is needed to understand the clinical implications of CT/NG coinfections. Future studies should investigate factors influencing anorectal CT/NG bacterial burden, transmissibility and susceptibility, including the function of pre-exposure prophylaxis and the rectal microbiota.
Authors
- Delia Onorini (ORCID: https://orcid.org/0000-0002-8783-837X)
- Cory Ann Leonard (ORCID: https://orcid.org/0000-0003-0711-5006)
- Benjamin Hampel (ORCID: https://orcid.org/0000-0002-5474-5927)
- Nicole Borel (ORCID: https://orcid.org/0000-0002-1556-9262)
- Nicola Low (ORCID: https://orcid.org/0000-0003-4817-8986)
- Hanna Marti (ORCID: https://orcid.org/0000-0002-8398-4708)
- Enrique Rayo (ORCID: https://orcid.org/0000-0002-4497-4339)
- Giulia Malingamba
Institutions
- University of Bern (CH)
- Henry M. Jackson Foundation (US)
- University of Zurich (CH)
- Prevention Institute (US)
- Institute of Social and Preventive Medicine (CH)
Publication Details
- Journal
- Sexually Transmitted Infections
- Published
- 2025-08-17
- DOI
- https://doi.org/10.1136/sextrans-2025-056579
- Primary Topic
- Reproductive tract infections research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung