Association of renal cortical thickness and renal function in patients with malignant hypertension with thrombotic microangiopathy: a biopsy-based cohort study from China

Smaller RCTs were correlated with a decline in renal function and deterioration of renal pathology. Furthermore, larger RCTs showed a better renal function improvement of ≥15% increase in eGFR in mHTN patients with TMA. RCT may be a predictive factor for renal damage in mHTN.

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Publication Details

Journal
BMJ Open
Published
2025-08-01
DOI
https://doi.org/10.1136/bmjopen-2024-096581
Citations
2
Primary Topic
Renal and Vascular Pathologies
Type
article
Field-Weighted Citation Impact
3.04

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article

Association of renal cortical thickness and renal function in patients with malignant hypertension with thrombotic microangiopathy: a biopsy-based cohort study from China

Xingji Lian, Shibo Wei, Zhaocai Zhou, Yunuo Wang et al.
2 citations
BMJ Open
Renal and Vascular Pathologies
3.04
article

Association of renal cortical thickness and renal function in patients with malignant hypertension with thrombotic microangiopathy: a biopsy-based cohort study from China

Xingji Lian, Shibo Wei, Zhaocai Zhou, Yunuo Wang, Rong Lian, Zhong Zhong, Wei Chen, Jianbo Li, Sheng Zhao, Feng He, Naya Huang, Shicong Yang
article en
2 citations

Abstract

Smaller RCTs were correlated with a decline in renal function and deterioration of renal pathology. Furthermore, larger RCTs showed a better renal function improvement of ≥15% increase in eGFR in mHTN patients with TMA. RCT may be a predictive factor for renal damage in mHTN.

BMJ OpenVol. 15(8)
Sun Yat-sen University (CN), Guangzhou First People's Hospital (CN), The First Affiliated Hospital, Sun Yat-sen University (CN), Stomatology Hospital (CN), South China University of Technology (CN), Guangzhou Medical University (CN)
National Natural Science Foundation of China, Sun Yat-sen University, Natural Science Foundation of Guangdong Province, National Health Commission of the People's Republic of China
Good health and well-being
Openalex Percentile: Top 8%
Renal and Vascular Pathologies
3.04
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Association of renal cortical thickness and renal function in patients with malignant hypertension with thrombotic microangiopathy: a biopsy-based cohort study from China — Xingji Lian, Shibo Wei, et al. · BMJ Open (2025) | TGRS Research Map | TGRS