Pharmacokinetic study of isavuconazonium in human plasma measured by HPLC-MS/MS and its use in healthy Chinese subjects
The validated HPLC-MS/MS method is rapid and reliable for therapeutic drug monitoring. Food affects absorption but not total exposure, guiding clinical dosing in Chinese populations.
Authors
- L. Qiu
- Lin Jie (ORCID: https://orcid.org/0000-0001-5244-3610)
- Yifang Chen (ORCID: https://orcid.org/0000-0002-4135-5508)
- Yuchen Su (ORCID: https://orcid.org/0000-0002-2492-1942)
- Yan Kong (ORCID: https://orcid.org/0000-0002-6368-2112)
- Yanli Zhou (ORCID: https://orcid.org/0000-0002-4591-3044)
- Yonghua Yu (ORCID: https://orcid.org/0000-0002-8752-9956)
Institutions
- Zhejiang Pharmaceutical College (CN)
Publication Details
- Journal
- Bioanalysis
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1080/17576180.2025.2548195
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Basic Public Welfare Research Program of Zhejiang Province