Short-term effects of oral dissolving film on halitosis and oral pathogenic bacteria: a pilot non-randomized controlled trial
ODF exhibited significant reductions in key halitosis-associated compounds and demonstrated antimicrobial activity against cariogenic bacteria. This suggests ODF may serve as a convenient alternative approach for both halitosis management and dental caries prevention. Further large-scale, randomized trials are warranted to confirm these preliminary findings. This study was registered in https://trialsearch.who.int (KCT0010244).
Authors
- Hye-Sung Kim (ORCID: https://orcid.org/0000-0003-1131-9992)
- Mu-Yeol Cho (ORCID: https://orcid.org/0000-0003-2499-7645)
- Young-Youn Kim (ORCID: https://orcid.org/0000-0002-0299-8447)
- Seung-Jo Yang (ORCID: https://orcid.org/0000-0001-7084-5816)
- Eun‐Mi Choi (ORCID: https://orcid.org/0000-0002-6039-7383)
- JW Kim (ORCID: https://orcid.org/0000-0002-0498-5762)
- Jeong-Sik Eom
- Ju-young Hwang
Institutions
- Korea Aerospace University (KR)
- STARmed (South Korea) (KR)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-08-19
- DOI
- https://doi.org/10.3389/fmicb.2025.1639960
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Korea National Institute of Health