Whole Brain Spectral Power Differences During Infancy Following Antenatal SARS‐CoV‐2 and Zika Virus Exposure: Findings From Cohorts in Boston, Massachusetts and San Juan, Puerto Rico
ZIKV exposure during pregnancy was associated with reductions in low-frequency EEG power, which may be indicative of disruptions in early brain maturation. SARS-CoV-2 exposure was associated with reductions in higher-frequency power, suggesting potential impairments on sensorimotor and cognitive integration. Increases in beta power by 12 months in the SARS-CoV-2 cohort indicate some recovery, although potential compounding and sleeper effects from early disruptions are possible.
Authors
- Andrea G. Edlow (ORCID: https://orcid.org/0000-0003-2915-5949)
- Dashiell D. Sacks (ORCID: https://orcid.org/0000-0003-2842-1301)
- Janet P. Near
- Charles A. Nelson (ORCID: https://orcid.org/0000-0002-4723-247X)
- Adriana S. Méndez Leal (ORCID: https://orcid.org/0000-0002-0147-9450)
- Viviane Valdes (ORCID: https://orcid.org/0000-0001-5809-3877)
- Carmen Zorrilla (ORCID: https://orcid.org/0000-0001-7740-1636)
Institutions
- Boston Children's Hospital (US)
- Harvard University (US)
- University of California, Los Angeles (US)
- University of Puerto Rico System (PR)
- Reproductive Science Center (US)
- Dana-Farber/Harvard Cancer Center (US)
Publication Details
- Journal
- International Journal of Developmental Neuroscience
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1002/jdn.70047
- Primary Topic
- Neonatal and fetal brain pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute on Drug Abuse
- National Institute of Allergy and Infectious Diseases
- National Institute on Minority Health and Health Disparities