Hepatic mucinous cystic neoplasm in a male patient: A case report

Hepatic mucinous cystic neoplasms (MCN) are rare cystic tumors that are predominantly observed in females, with a low incidence rate in males. To date, few cases of aggressive MCN have been reported in male patients. The current study reports the case of a 74-year-old male patient who presented to Xixi Hospital with abdominal distension. Results of imaging investigations revealed a cystic lesion in the liver and histopathological examination demonstrated positive staining for caudal type homeobox 2, cytokeratin 20, postmeiotic segregation increased 2, progesterone receptor and α-inhibin, leading to a definitive diagnosis of hepatic mucinous cystadenoma. Collectively, the results of the present article demonstrated that hepatic MCN should be considered in the differential diagnosis of cystic liver lesions, including in male patients. A comprehensive evaluation that integrates clinical characteristics, and imaging and histopathological findings is essential for the optimal management of this condition.

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Publication Details

Journal
Experimental and Therapeutic Medicine
Published
2025-08-19
DOI
https://doi.org/10.3892/etm.2025.12952
Primary Topic
Genetic and Kidney Cyst Diseases
Type
article
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article

Hepatic mucinous cystic neoplasm in a male patient: A case report

Xiantu Zhang, Wanneng Pan, Qinming Hou, Bo Wu et al.
Experimental and Therapeutic Medicine
Genetic and Kidney Cyst Diseases
article

Hepatic mucinous cystic neoplasm in a male patient: A case report

Xiantu Zhang, Wanneng Pan, Qinming Hou, Bo Wu, Zongyuan Zhan, Yuandong Zhu
article en

Abstract

Hepatic mucinous cystic neoplasms (MCN) are rare cystic tumors that are predominantly observed in females, with a low incidence rate in males. To date, few cases of aggressive MCN have been reported in male patients. The current study reports the case of a 74-year-old male patient who presented to Xixi Hospital with abdominal distension. Results of imaging investigations revealed a cystic lesion in the liver and histopathological examination demonstrated positive staining for caudal type homeobox 2, cytokeratin 20, postmeiotic segregation increased 2, progesterone receptor and α-inhibin, leading to a definitive diagnosis of hepatic mucinous cystadenoma. Collectively, the results of the present article demonstrated that hepatic MCN should be considered in the differential diagnosis of cystic liver lesions, including in male patients. A comprehensive evaluation that integrates clinical characteristics, and imaging and histopathological findings is essential for the optimal management of this condition.

Experimental and Therapeutic MedicineVol. 30(4)
Hangzhou Xixi hospital (CN)
Gender equality
Openalex Percentile: Top 77%
Genetic and Kidney Cyst Diseases
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Hepatic mucinous cystic neoplasm in a male patient: A case report — Xiantu Zhang, Wanneng Pan, et al. · Experimental and Therapeutic Medicine (2025) | TGRS Research Map | TGRS