Leukemia Burden Impacts the Efficacy and Toxicity of Blinatumomab in Pediatric B‐Cell Acute Lymphoblastic Leukemia
Overall, these results indicate that blinatumomab is effective and well tolerated. Patients with a lower leukemia burden before blinatumomab administration tend to have better OS and EFS with fewer AEs.
Authors
- Shaoyan Hu (ORCID: https://orcid.org/0000-0002-5183-2259)
- Wenhui Yan (ORCID: https://orcid.org/0000-0001-6976-0137)
- Yunyan He (ORCID: https://orcid.org/0000-0001-7181-4878)
- Xue Tang (ORCID: https://orcid.org/0000-0002-3983-979X)
- Wenting Hu (ORCID: https://orcid.org/0000-0003-4639-9056)
- Yalan You
- Ming Sun (ORCID: https://orcid.org/0000-0002-6416-312X)
- Wenjin Gao (ORCID: https://orcid.org/0000-0002-9121-3890)
- Xiaojun Xu (ORCID: https://orcid.org/0000-0003-1388-2535)
- Lihua Yang (ORCID: https://orcid.org/0000-0002-6293-4816)
- Yufeng Liu (ORCID: https://orcid.org/0000-0003-2653-3510)
- Dun‐hua Zhou (ORCID: https://orcid.org/0000-0003-0179-5223)
- Yongmin Tang
- Lili Song (ORCID: https://orcid.org/0000-0002-3290-3330)
- Yang Wenyu
- Yan Gu
Institutions
- Sun Yat-sen University (CN)
- Hunan Normal University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Soochow University (CN)
- Shanghai Children's Medical Center (CN)
- Sun Yat-sen Memorial Hospital (CN)
- Zhengzhou Children's Hospital (CN)
- Children's Hospital of Zhejiang University (CN)
- Zhujiang Hospital (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
- Hunan Children's Hospital (CN)
- Xi’an Children’s Hospital (CN)
- Wuhan Children's Hospital (CN)
- Hunan Provincial People's Hospital (CN)
- Institute of Hematology & Blood Diseases Hospital (CN)
- Children's Hospital of Suzhou University (CN)
- Shenzhen Children's Hospital (CN)
- Shandong Provincial QianFoShan Hospital (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
- Shandong First Medical University (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1002/cam4.71159
- Citations
- 1
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 1.88