Autoencoder-Assisted Stacked Ensemble Learning for Lymphoma Subtype Classification: A Hybrid Deep Learning and Machine Learning Approach
This study demonstrates a highly accurate and reliable approach to lymphoma classification by using autoencoder-assisted ensemble learning, reducing the misclassification rate and significantly enhancing the accuracy of diagnosis. AI-based models are designed to assist pathologists by providing interpretable outputs such as class probabilities and visualizations (e.g., Grad-CAM), enabling them to understand and validate predictions in the diagnostic workflow. Future studies should enhance computational efficacy and conduct multi-centre validation studies to confirm the model's generalizability on extensive collections of histopathological datasets.
Authors
- Pius Adewale Owolawi (ORCID: https://orcid.org/0000-0002-5781-5054)
- Etienne Van Wyk (ORCID: https://orcid.org/0000-0002-0436-2741)
- Chunling Tu
- Roseline Oluwaseun Ogundokun (ORCID: https://orcid.org/0000-0002-2592-2824)
Institutions
- Tshwane University of Technology (ZA)
Publication Details
- Journal
- Tomography
- Published
- 2025-08-18
- DOI
- https://doi.org/10.3390/tomography11080091
- Citations
- 2
- Primary Topic
- AI in cancer detection
- Type
- article
- Field-Weighted Citation Impact
- 4.96