Safety of internal thoracic artery use in patients with prior mediastinal radiation undergoing coronary artery bypass grafting: a Maryland statewide propensity-matched analysis
In this large retrospective cohort, prior mediastinal radiation was not associated with an increased risk of perioperative adverse events in patients undergoing CABG receiving ITA grafts. These findings demonstrate no evidence of safety concerns with the use of ITA grafting in patients with prior radiation and challenge the practice of excluding these patients from arterial revascularisation strategies.
Authors
- Diane Alejo (ORCID: https://orcid.org/0000-0003-2751-9577)
- Alice L. Zhou (ORCID: https://orcid.org/0000-0001-6593-3985)
- Duke E. Cameron (ORCID: https://orcid.org/0000-0001-7193-1329)
- Jessica Blair Briscoe (ORCID: https://orcid.org/0000-0003-3308-4215)
- Zachary E Darby
- James S. Gammie (ORCID: https://orcid.org/0000-0003-2522-8039)
- Rawn Salenger (ORCID: https://orcid.org/0009-0000-6895-1046)
- Hanghang Wang (ORCID: https://orcid.org/0000-0002-9432-0261)
- Sari D. Holmes (ORCID: https://orcid.org/0000-0001-6411-0055)
- Ifeanyi Chinedozi (ORCID: https://orcid.org/0000-0001-7012-5931)
- Jennifer S. Lawton (ORCID: https://orcid.org/0000-0002-0825-6591)
- Armaan F. Akbar (ORCID: https://orcid.org/0000-0002-4255-9019)
- Deven Patel (ORCID: https://orcid.org/0000-0002-1154-3444)
- Glenn Whitman
Institutions
- Johns Hopkins Hospital (US)
- St. Joseph Medical Center (US)
Publication Details
- Journal
- Heart
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1136/heartjnl-2025-325949
- Primary Topic
- Congenital Heart Disease Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00