The Impact of Using Different Cationic Polymers on the Formation of Efficient Lipopolyplexes for pDNA Delivery
Overall, this study demonstrates that lipopolyplexes are a valid platform for pDNA delivery, with PEI lipopolyplexes being the best performing formulation, and that the type of cationic polymer plays a major role in the nanoparticles intercellular trafficking.
Authors
- Valerio Magnaghi (ORCID: https://orcid.org/0000-0002-6903-7042)
- Giulia Anderluzzi (ORCID: https://orcid.org/0000-0001-7363-9137)
- Elena Del Favero (ORCID: https://orcid.org/0000-0002-6584-1869)
- Francesco Cilurzo (ORCID: https://orcid.org/0000-0003-3560-291X)
- Loris Rizzello (ORCID: https://orcid.org/0000-0002-8230-853X)
- Silvia Franzè (ORCID: https://orcid.org/0000-0003-2231-031X)
- Tasnim Mohamed (ORCID: https://orcid.org/0000-0002-1144-4876)
- Giorgia Moschetti (ORCID: https://orcid.org/0000-0001-7763-4421)
Institutions
- University of Milan (IT)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-08-01
- DOI
- https://doi.org/10.2147/ijn.s513568
- Citations
- 3
- Primary Topic
- RNA Interference and Gene Delivery
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- European Synchrotron Radiation Facility