Development of a lung perfusion automated quantitative model based on dual-energy CT pulmonary angiography in patients with chronic pulmonary thromboembolism
Right heart catheterization for definitive diagnosis of chronic pulmonary thromboembolism (CPE) is invasive. PerAIDE-based perfusion defects correlated with disease severity to aid CPE-treatment assessment. CTEPH demonstrates severe perfusion defects, while CTEPD displays predominantly reduced perfusion. PerAIDE employs a U-Net-based adaptive threshold method, which achieves alignment with and faster processing relative to manual evaluation.
Authors
- Linfeng Xi (ORCID: https://orcid.org/0000-0001-5702-4159)
- Yishan Li
- Yong Cheng (ORCID: https://orcid.org/0000-0001-9590-9548)
- Jie Du (ORCID: https://orcid.org/0000-0003-3400-9559)
- Min Liu (ORCID: https://orcid.org/0000-0003-1298-4441)
- Shuai Zhang (ORCID: https://orcid.org/0000-0002-2916-3394)
- Zhu Zhang (ORCID: https://orcid.org/0000-0001-5009-4680)
- Qiang Huang (ORCID: https://orcid.org/0000-0001-5269-4161)
- Jianping Wang (ORCID: https://orcid.org/0000-0001-8812-8428)
- Yunxia Zhang (ORCID: https://orcid.org/0000-0002-5637-6782)
- Hongyi Wang (ORCID: https://orcid.org/0000-0003-0125-6430)
- Dingyi Wang (ORCID: https://orcid.org/0000-0002-5754-029X)
- Anqi Liu (ORCID: https://orcid.org/0000-0002-9432-4836)
- Yifei Ni
- Qian Gao (ORCID: https://orcid.org/0000-0001-6876-4435)
- Jing Wen
- Wanmu Xie (ORCID: https://orcid.org/0000-0002-6686-3517)
Institutions
- Shanxi Medical University (CN)
- Capital Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- China-Japan Friendship Hospital (CN)
- Peking Union Medical College Hospital (CN)
- Beijing University of Chemical Technology (CN)
Publication Details
- Journal
- Insights into Imaging
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1186/s13244-025-02067-6
- Citations
- 3
- Primary Topic
- Advanced X-ray and CT Imaging
- Type
- article
- Field-Weighted Citation Impact
- 2.02
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China