Neuroblastoma in Infants: Long‐Term Survival From INES Protocols A SIOPEN Study
Survival in patients less than 12 months remains excellent and stable even at long term, as a 10-year follow-up did not change the number of events. However, survival in MYCN-amplified tumors remained poor. Patients with metastatic tumors require accurate risk stratification. For each treatment group, there was no significant difference in long-term outcomes compared with previous publications from INES. No lethal toxicity affecting long-term survival occurred.
Authors
- Benoît Dumont (ORCID: https://orcid.org/0000-0001-8331-3480)
- Ruth Lydia Ladenstein (ORCID: https://orcid.org/0000-0001-6548-3873)
- Dominique Valteau‐Couanet (ORCID: https://orcid.org/0009-0001-9880-2241)
- Kate Wheeler (ORCID: https://orcid.org/0009-0006-6707-2609)
- Vanessa Segura (ORCID: https://orcid.org/0000-0002-0410-9674)
- Andrea Di Cataldo (ORCID: https://orcid.org/0000-0002-4509-3066)
- Adela Cañete (ORCID: https://orcid.org/0000-0002-5669-5097)
- Riccardo Haupt (ORCID: https://orcid.org/0000-0003-0571-8460)
- Anne Sophie Defachelles (ORCID: https://orcid.org/0000-0002-4277-9871)
- Marion Gambart (ORCID: https://orcid.org/0000-0002-4364-5170)
- Katia Mazzocco (ORCID: https://orcid.org/0000-0002-6599-5681)
- Claudia Pasqualini (ORCID: https://orcid.org/0000-0002-1113-2792)
- Bénédicte Brichard (ORCID: https://orcid.org/0000-0003-2765-1711)
- Maja Beck‐Popovic (ORCID: https://orcid.org/0000-0001-9502-5697)
- Gudrun Schleiermacher (ORCID: https://orcid.org/0000-0002-0133-5879)
- D. Ramal
- Alberto Garaventa (ORCID: https://orcid.org/0000-0002-5368-6363)
- Carole Coze (ORCID: https://orcid.org/0000-0003-3996-3835)
- Caroline Munzer
- Stefania Sorrentino (ORCID: https://orcid.org/0000-0001-7381-0133)
- Ana Lacerda (ORCID: https://orcid.org/0000-0003-3387-3521)
- Julie Savagner (ORCID: https://orcid.org/0000-0002-3348-350X)
Institutions
- Cliniques Universitaires Saint-Luc (BE)
- Inserm (FR)
- Aix-Marseille Université (FR)
- Université Paris Sciences et Lettres (FR)
- Istituto Giannina Gaslini (IT)
- Institut Gustave Roussy (FR)
- John Radcliffe Hospital (GB)
- Hospital Universitari i Politècnic La Fe (ES)
- University of Catania (IT)
- Institut d’Hématologie et d’Oncologie Pédiatrique (FR)
- Instituto Português de Oncologia Francisco Gentil (PT)
- St Anna Children's Hospital (AT)
- Mother Hospital (IN)
- Centre Oscar Lambret (FR)
- Hôpital des Enfants (FR)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Hôpital de la Timone (FR)
- Instituto de Investigación Sanitaria La Fe (ES)
- Institut Curie (FR)
- University of Lausanne (CH)
Publication Details
- Journal
- Pediatric Blood & Cancer
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1002/pbc.31982
- Citations
- 2
- Primary Topic
- Neuroblastoma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.78
Funders
- Fondazione Italiana per la Lotta al Neuroblastoma
- Ministero della Salute