Adipokines and Associations With Incident Osteoporotic Fracture in Patients With Rheumatoid Arthritis
Elevations in adipokines are associated with an increased risk of fracture in patients with RA, independent of other established risk factors including BMI, smoking, and prednisone use. This supports further investigation to understand whether this association is related to altered body composition or disrupted metabolic pathways.
Authors
- Katherine D. Wysham (ORCID: https://orcid.org/0000-0001-8707-7649)
- Punyasha Roul
- Aleksander Lenert (ORCID: https://orcid.org/0000-0003-2129-3263)
- Geoffrey M. Thiele (ORCID: https://orcid.org/0000-0001-5688-8596)
- Michael George (ORCID: https://orcid.org/0000-0002-0398-2308)
- Brian C. Sauer (ORCID: https://orcid.org/0000-0002-3546-3051)
- Ted R. Mikuls (ORCID: https://orcid.org/0000-0002-0897-2272)
- Bryant R. England (ORCID: https://orcid.org/0000-0002-9649-3588)
- Joshua F. Baker (ORCID: https://orcid.org/0000-0003-0170-028X)
- Hannah F. Brubeck (ORCID: https://orcid.org/0009-0007-1964-5318)
Institutions
- University of Utah (US)
- VA Puget Sound Health Care System (US)
- Lake City VA Medical Center (US)
- Iowa City VA Health Care System (US)
- Philadelphia VA Medical Center (US)
- VA Nebraska Western Iowa Health Care System (US)
- University of Nebraska Medical Center (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Arthritis Care & Research
- Published
- 2025-08-19
- DOI
- https://doi.org/10.1002/acr.25632
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Defense
- U.S. Department of Veterans Affairs
- Rheumatology Research Foundation
- National Institute of General Medical Sciences