Phillyrin prevents calcium oxalate kidney stones through the PPARγ signaling pathway
The present study demonstrated that the potential efficacy of phillyrin on alleviating CaOx kidney stone formation and associated oxidative stress. PPARγ signaling is the possible mechanism of action of phillyrin in controlling nephrolithiasis-triggered apoptosis.
Authors
- Xiaohan Chu (ORCID: https://orcid.org/0000-0001-6045-175X)
- Enxu Xie
- Bo Zhou (ORCID: https://orcid.org/0000-0002-6411-9372)
- Shuaiqi Liu (ORCID: https://orcid.org/0000-0001-7520-8226)
- Shengwei Zhang (ORCID: https://orcid.org/0000-0001-9153-4398)
- Xingkang Chang
Institutions
- Second Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Renal Failure
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1080/0886022x.2025.2486559
- Primary Topic
- Kidney Stones and Urolithiasis Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00